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William J Jusko Selected Research

Bone Resorption

10/2018Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.

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William J Jusko Research Topics

Disease

17Rheumatoid Arthritis
05/2020 - 08/2008
15Disease Progression
01/2017 - 01/2008
14Pancreatic Neoplasms (Pancreatic Cancer)
01/2024 - 01/2013
12Neoplasms (Cancer)
01/2024 - 05/2009
10Body Weight (Weight, Body)
06/2021 - 02/2002
10Inflammation (Inflammations)
01/2017 - 02/2011
8Experimental Arthritis
01/2017 - 08/2008
8Edema (Dropsy)
01/2017 - 08/2008
7Insulin Resistance
10/2018 - 01/2005
6Arthritis (Polyarthritis)
10/2018 - 08/2008
4Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
04/2024 - 10/2018
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 05/2002
4Type 2 Diabetes Mellitus (MODY)
01/2014 - 02/2011
3Adenocarcinoma
01/2024 - 05/2013
3Obesity
06/2020 - 01/2017
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2013 - 05/2010
3Hyperinsulinism (Hyperinsulinemia)
06/2011 - 01/2009
2COVID-19
01/2023 - 01/2023
2Cytokine Release Syndrome
01/2023 - 01/2023
2Cerebral Palsy (Spastic Diplegia)
01/2018 - 05/2014
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2018 - 05/2010
2Endotoxemia
01/2017 - 03/2005
2Weight Gain
06/2012 - 12/2011
2Chronic Disease (Chronic Diseases)
01/2012 - 06/2011
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
10/2023
1Autoimmune Hepatitis
01/2022
1Brain Injuries (Brain Injury)
01/2020
1Autoimmune Diseases (Autoimmune Disease)
01/2019
1Crohn Disease (Crohn's Disease)
10/2018
1Bone Resorption
10/2018

Drug/Important Bio-Agent (IBA)

12GemcitabineFDA Link
01/2024 - 09/2013
11Glucose (Dextrose)FDA LinkGeneric
01/2013 - 01/2005
10Adrenal Cortex Hormones (Corticosteroids)IBA
01/2019 - 05/2002
10CollagenIBA
09/2018 - 08/2008
9Dexamethasone (Maxidex)FDA LinkGeneric
01/2023 - 11/2003
9Insulin (Novolin)FDA Link
01/2013 - 01/2005
8MethylprednisoloneFDA LinkGeneric
01/2019 - 11/2003
6Proteins (Proteins, Gene)FDA Link
01/2024 - 06/2015
6CytokinesIBA
01/2023 - 05/2002
6Messenger RNA (mRNA)IBA
01/2014 - 04/2008
5Prednisolone (Predate)FDA LinkGeneric
03/2005 - 05/2002
4VBP15 compoundIBA
04/2024 - 10/2018
4TrabectedinIBA
01/2024 - 01/2016
4Biomarkers (Surrogate Marker)IBA
10/2018 - 06/2011
4birinapantIBA
10/2018 - 10/2015
4Paclitaxel (Taxol)FDA LinkGeneric
01/2018 - 08/2002
4Interleukin-6 (Interleukin 6)IBA
01/2016 - 08/2008
3Drug CombinationsIBA
01/2024 - 01/2018
3GlucocorticoidsIBA
10/2018 - 01/2005
3Etanercept (Enbrel)FDA Link
10/2018 - 07/2011
3Monoclonal AntibodiesIBA
01/2018 - 05/2010
3InterleukinsIBA
01/2018 - 08/2008
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2017 - 08/2008
3salicylsalicylic acid (salsalate)IBA
01/2014 - 12/2011
3EverolimusFDA Link
05/2013 - 01/2013
3Sorafenib (BAY 43-9006)FDA Link
05/2013 - 01/2013
3CorticosteroneIBA
08/2008 - 07/2008
2LipopolysaccharidesIBA
01/2023 - 03/2005
2SteroidsIBA
06/2020 - 02/2002
2Contraceptive Agents (Contraceptives)IBA
06/2020 - 01/2017
2tofacitinibIBA
05/2020 - 01/2019
2Inhibitor of Apoptosis ProteinsIBA
01/2018 - 10/2015
2BaclofenFDA LinkGeneric
01/2018 - 05/2014
2Naproxen (Naprosyn)FDA LinkGeneric
01/2017 - 01/2017
2Blood Proteins (Serum Proteins)IBA
01/2017 - 06/2003
2Phosphotransferases (Kinase)IBA
05/2013 - 01/2013
2Immunosuppressive Agents (Immunosuppressants)IBA
05/2013 - 09/2004
2TOR Serine-Threonine KinasesIBA
05/2013 - 01/2013
2otelixizumabIBA
11/2010 - 05/2010
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
09/2010 - 04/2007
2Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
08/2008 - 08/2008
2Therapeutic UsesIBA
06/2008 - 06/2003
2Interleukin-10 (Interleukin 10)IBA
03/2005 - 05/2002
1Cytochrome P-450 CYP3AIBA
04/2024
1Uridine Diphosphate (UDP)IBA
04/2024
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2024
1IntegrinsIBA
01/2024
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2024
1ProteomeIBA
10/2023
1Nicardipine (Dagan)FDA LinkGeneric
10/2023
1Oxygen (Dioxygen)IBA
01/2023
1Toll-Like Receptor 4IBA
01/2023
1Phosphodiesterase InhibitorsIBA
01/2022
1Metformin (Glucophage)FDA LinkGeneric
06/2021
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2021
1Hormones (Hormone)IBA
06/2020
1inter-alpha-inhibitorIBA
01/2020
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2020
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
10/2019
1Liposomes (Liposome)IBA
10/2019
1DystrophinIBA
01/2019
1Janus Kinase InhibitorsIBA
01/2019
1Janus KinasesIBA
01/2019
1Combined Oral ContraceptivesIBA
01/2019

Therapy/Procedure

9Therapeutics
01/2023 - 09/2004
3Drug Therapy (Chemotherapy)
01/2024 - 05/2002
2Hemodilution
06/2012 - 12/2008
1Postcoital Contraception (Emergency Contraception)
06/2020
1Hormonal Contraception
06/2020
1Lasers (Laser)
10/2019